Thursday, October 20, 2011

Common cellular and molecular mechanisms in obesity and drug addiction

Common cellular and molecular mechanisms in obesity and drug addiction

Nature Reviews Neuroscience 12, 638 (2011). doi:10.1038/nrn3105

Author: Paul J. Kenny

The hedonic properties of food can stimulate feeding behaviour even when energy requirements have been met, contributing to weight gain and obesity. Similarly, the hedonic effects of drugs of abuse can motivate their excessive intake, culminating in addiction. Common brain substrates regulate the hedonic properties






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