Friday, December 28, 2012

Benefits of early aneurysm surgery: Southern Iran experience

Abdolkarim Rahmanian, Mohammad Jamali, Ali Razmkon, Juri Kivelev, Rossana Romani, Ehsan-Ali Alibai, Juha Hernesniemi

Surgical Neurology International 2012 3(1):156-156

Background: Neurovascular surgery has been practiced in Shiraz, the main referral center of the Southern Iran, for over 30 years; however, the trend has accelerated tremendously in recent years following subspecialization of neurovascular surgery in Shiraz, Department of Neurosurgery. Over 100 patients are operated each year, and nearly all are addressed during the first 72 hours after presentation. Methods: In this paper, we focus on the description of techniques we apply for early clipping of ruptured intracranial aneurysms in the anterior circulation. Improvements in outcome, mortality, and rebleeding rates are also discussed. Results: Mortality and rebleeding rates have declined significantly since the institution of new techniques. Conclusion: The establishment of early surgery for ruptured anterior circulation aneurysms through the lateral supraorbital approach along with specific anesthetic protocol has resulted in significant improvement of morbidity, mortality, and rebleeding rates at our department.





Thursday, December 27, 2012

Importance of recognizing sentinel headache Pereira JL, de Albuquerque LA, Dellaretti M, de Carvalho GT, Vieira G, Rocha MI, Loures LL, Christo PP, de Sousa AA - Surg Neurol Int


ORIGINAL ARTICLE
Surg Neurol Int 2012,  3:162

Importance of recognizing sentinel headache

1 Neurology and Neurosurgery Service, Santa Casa Hospital, Belo Horizonte, Minas Gerais, Brazil
2 Neurology and Neurosurgery Service, Santa Casa Hospital, Belo Horizonte, Minas Gerais; Department of Neurosurgery, Faculty of Medical Sciences of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil3 Medical Student, Universidade Federal de Minas Gerais, Minas Gerais, Brazil4 Neurology and Neurosurgery Service and Graduate and Research Program, Santa Casa Hospital, Belo Horizonte, Minas Gerais, Brazil5 Neurology and Neurosurgery Service and Graduate and Research Program, Santa Casa Hospital, Belo Horizonte, Minas Gerais; Department of Neurosurgery, Faculty of Medical Sciences of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Date of Submission12-Aug-2012
Date of Acceptance23-Oct-2012
Date of Web Publication26-Dec-2012

    

Correspondence Address:
Gerival Vieira
Neurology and Neurosurgery Service, Santa Casa Hospital, Belo Horizonte, Minas Gerais 
Brazil
Login to access the Email id

© 2012 Pereira et al; This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI10.4103/2152-7806.105101

Get Permissions

   Abstract 

Background: Sentinel headache (SH) is a kind of secondary headache and is characterized as sudden, intense, and persistent, preceding spontaneous subarachnoid hemorrhage (SAH) by days or weeks.
Methods: Eighty-nine consecutive patients with a diagnosis of spontaneous SAH were evaluated following admission to the Neurosurgical Service at Santa Casa Hospital, Belo Horizonte, between December 2009 and December 2010.
Results: Out of the 89 patients, 64 (71.9%) were women. Mean age was 48.9 years (SD ± 13.4, ranging from 18 to 85 years). Twenty-four patients (27.0%) presented SH, which occurred, in average, 10.6 days (SD ± 13.5) before a SAH. No statistically significant differences were observed between the presence of SH and gender, arterial hypertension and migraine ( P > 0.05), Glasgow Comma Scale (GCS) and World Federation of Neurological Surgeons (WFNS) scale at admission.
Conclusion: The prevalence of SH was 27% in this study but no related factors were identified. Therefore, further clarification of this important entity is required so as to facilitate its recognition in emergency services and improve the prognosis of patients with cerebral aneurysms.

Keywords: Intracranial aneurysm, sentinel headache, subarachnoid hemorrhage


How to cite this article:
Pereira JL, de Albuquerque LA, Dellaretti M, de Carvalho GT, Vieira G, Rocha MI, Loures LL, Christo PP, de Sousa AA. Importance of recognizing sentinel headache. Surg Neurol Int 2012;3:162

How to cite this URL:
Pereira JL, de Albuquerque LA, Dellaretti M, de Carvalho GT, Vieira G, Rocha MI, Loures LL, Christo PP, de Sousa AA. Importance of recognizing sentinel headache. Surg Neurol Int [serial online] 2012 [cited 2012 Dec 27];3:162. Available from: http://www.surgicalneurologyint.com/text.asp?2012/3/1/162/105101

Wednesday, December 26, 2012

Skin closure in vascular neurosurgery: A prospective study on absorbable intradermal suture versus nonabsorbable suture - Surg Neurol Int


   Click here to download free Android Application for this and other journals       Click here to view optimized website for mobile devices       Journal is indexed with PubMed


 
Previous article  Table of Contents   Next article
ORIGINAL ARTICLE
Surg Neurol Int 2012,  3:94

Skin closure in vascular neurosurgery: A prospective study on absorbable intradermal suture versus nonabsorbable suture

1 Department of Neurosurgery, Santa Casa Hospital of Belo Horizonte, MG, Brazil
2 Facult of Medicine, Federal University of Minas Gerais (UFMG), MG, Brazil3 Department of Neurosurgery, Santa Casa Hospital of Belo Horizonte, MG; Lecturer at the Post-graduate and Research Program at Santa Casa Hospital of Belo Horizonte, MG, Brazil

Date of Submission20-Jun-2012
Date of Acceptance06-Jul-2012
Date of Web Publication21-Aug-2012

    

Correspondence Address:
Gerival Vieira
Department of Neurosurgery, Santa Casa Hospital of Belo Horizonte, MG 
Brazil
Login to access the Email id

© 2012 Pereira et al; This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI10.4103/2152-7806.99941

Get Permissions

   Abstract 

Background: The craniotomy performed with minimal hair removal and closure with intradermal suture alone is an option in neurosurgical procedures, which can help faster psychological recovery of the patient, as it allows a better cosmetic result. This study is aimed at evaluating if such method is safe and effective, compared with continuous skin sutures with 2-0 nylon. 
Methods: We analyzed the sutures in 117 patients undergoing craniotomies for cerebral aneurysm clipping. In the case group (n = 49), closure of the scalp was performed only with intradermal absorbable sutures using wire Monocryl; 2-0. In the control group (n = 68), closure was performed with continuous suture using 2-0 nylon. 
Results: The case group was composed of 49 patients in whom just intradermal suture was performed. One (2.2%) patient developed wound infection and was given proper medical treatment. No cases of dehiscence or cerebrospinal fluid leaks were observed. The control group was composed of 68 patients in whom the skin was closed with 2-0 nylon continuous suture. Three (5.3%) patients developed wound infection and were given proper medical treatment. There were no cases of wound dehiscence. The overall infection rate in the control group was 4%. There was no statistically significant difference in the number of wound infections between the two groups (P = 0.73).
Conclusion: The closure with intradermal suture alone in craniotomies is as safe as the traditional skin closure with nylon sutures, besides eliminating the need for suture removal and providing a cosmetic advantage.

Keywords: Intracranial aneurysm, intradermal suture, skin closure


How to cite this article:
Pereira JL, Vieira G, Freitas de Albuquerque LA, Mendes GC, Salles LR, Ferreira de Souza AF, Dellaretti M, de Sousa AA. Skin closure in vascular neurosurgery: A prospective study on absorbable intradermal suture versus nonabsorbable suture. Surg Neurol Int 2012;3:94

How to cite this URL:
Pereira JL, Vieira G, Freitas de Albuquerque LA, Mendes GC, Salles LR, Ferreira de Souza AF, Dellaretti M, de Sousa AA. Skin closure in vascular neurosurgery: A prospective study on absorbable intradermal suture versus nonabsorbable suture. Surg Neurol Int [serial online] 2012 [cited 2012 Dec 26];3:94. Available from: http://www.surgicalneurologyint.com/text.asp?2012/3/1/94/99941

Decompressive hemicraniectomy after malignant middle cerebral artery infarction: rationale and contr

Neurosurgical FOCUS, Volume 30, Issue 6, Page E18, June 2011.

Omar M. Arnaout, M.D., Salah G. Aoun, M.D., H. Hunt Batjer, M.D., and Bernard R. Bendok, M.D. Malignant middle cerebral artery stroke carries a very poor prognosis. Significant retrospective data support the hypothesis that decompressive hemicraniectomy decreases mortality rates due to this disease entity. Recently, 3 randomized controlled studies have been published and shed light on these issues and enhance the quality of evidence revolving around this procedure. In this review, the rationale, risks, benefits, and unanswered questions related to hemicraniectomy for acute ischemic stroke are reviewed with an emphasis on how 3 randomized trials have influenced knowledge on this life-saving yet controversial procedure. Further randomized studies are needed to clarify lingering questions regarding age indications and impact on quality of life.





Interobserver Variability of Grading Scales for Aneurysmal Subarachnoid Hemorrhage [Original Contrib

Background and Purpose—

Worldwide, different scales are used to assess the clinical condition on admission after aneurysmal subarachnoid hemorrhage. In addition to the prognostic value, the inter-rater variability should be taken into account when deciding which scale preferably should be used. We assessed the interobserver agreement of the commonly used World Federation of Neurological Surgeons, the Hunt and Hess, and the Prognosis on Admission of Aneurysmal Subarachnoid Hemorrhage scales.

Methods—

In a cohort of 50 subarachnoid hemorrhage patients, 103 paired assessments were performed on the 3 admission scales by 2 independent observers per assessment with a total of 57 different raters. Patients were assessed during the first week after the hemorrhage. The interobserver agreement was calculated using quadratic (weighted) kappa statistics.

Results—

The weighted kappa value of the Prognosis on Admission of Aneurysmal Subarachnoid Hemorrhage scale was 0.64 (95% CI, 0.49–0.79), of the World Federation of Neurological Surgeons scale was 0.60 (95% CI, 0.48–0.73), and of the Hunt and Hess scale was 0.48 (95% CI, 0.36–0.59).

Conclusions—

The Hunt and Hess scale showed the lowest interobserver agreement, whereas agreement of the World Federation of Neurological Surgeons and Prognosis on Admission of Aneurysmal Subarachnoid Hemorrhage scales was similar with overlapping CI.






Meta-analysis of instrumented posterior interbody fusion versus instrumented posterolateral fusion i

Journal of Neurosurgery: Spine, Volume 15, Issue 3, Page 295-310, September 2011.
Object The authors compared the effectiveness of instrumented posterior lumbar interbody fusion (iPLIF) and instrumented posterolateral fusion (iPLF) for the treatment of low-back pain (LBP) due to degenerative lumbar disease. Methods Relevant randomized controlled trials (RCTs) and comparative observational studies through December 2009 were identified using a retrieval strategy of sensitive and specific searches. The study design, participant characteristics, interventions, follow-up rate and period, and outcomes were abstracted after the assessment of methodological quality of the trials. Analyses were performed following the method guidelines of the Cochrane Back Review Group. Results Nine studies were identified—3 RCTs and 6 comparative observational studies. No significant difference was found between the 2 fusion procedures in the global assessment of clinical outcome (OR 1.51, 95% CI 0.71–3.22, p = 0.29) and complication rate (OR 0.55, 95% CI 0.16–1.86, p = 0.34). Both techniques were effective in reducing pain and improving functional disability, as well as restoring intervertebral disc height. Instrumented PLIF was more effective in achieving solid fusion (OR 2.60, 95% CI 1.35–5.00, p = 0.004), a lower reoperation rate (OR 0.20, 95% CI 0.03–1.29, p = 0.09), and better restoration of segmental angle and lumbar lordotic angle than iPLF. There were no significant differences between the fusion methods regarding blood loss (weighted mean difference –179.63, 95% CI –516.42 to 157.15, p = 0.30), and operating time (weighted mean difference 8.03, 95% CI –45.46 to 61.53, p = 0.77). Conclusions The authors' analysis provided moderate-quality evidence that iPLIF has the advantages of higher fusion rate and better restoration of spinal alignment over iPLF. No significant differences were identified between iPLIF and iPLF concerning clinical outcome, complication rate, operating time, and blood loss.





Tuesday, December 25, 2012

The effect of methylprednisolone intravenous infusion on the expression of ciliary neurotrophic fact

Available online 23 December 2012
Publication year: 2012
Source:The Spine Journal

Background context Methylprednisolone (MP) infusion after acute spinal cord injury (SCI) remains controversial despite large randomized studies, including the National Acute Spinal Cord Injury Studies (NASCIS). Purpose To determine the effect of NASCIS protocol MP infusion on the expression of ciliary neurotrophic factor (CNTF), a neuroprotective cytokine, in a rat model after SCI. Study design Animal laboratory study. Methods Thirty rats were randomized into an MP infusion group (intravenous [IV]-MP) versus normal saline (NS) control group (IV-NS) after a standardized SCI. Ciliary neurotrophic factor expression was measured by reverse transcription-polymerase chain reaction at 6, 12, 24, 48, and 72 hours post-SCI. Results Mean CNTF expression was diminished in the MP group at 12 (p=.006) and 24 (p=.008) hours postinjury compared with the control group. Expression of CNTF was not significantly different between the groups at 6, 48, and 72 hours post-SCI. Conclusions Standardized MP infusion post-SCI reduces CNTF activation in a rat SCI model. Further study is needed to determine if this effect is seen in human SCIs.






Brain Imaging Insight Into Cannabis As A Pain Killer

The pain relief offered by cannabis varies greatly between individuals, a brain imaging study carried out at the University of Oxford suggests. The researchers found that an oral tablet of THC, the psychoactive ingredient in cannabis, tended to make the experience of pain more bearable, rather than actually reduce the intensity of the pain...





Cervical Spinal Cord Infarction Following Cervical Spine Decompressive Surgery

Available online 23 December 2012
Publication year: 2012
Source:World Neurosurgery

Objective Spinal cord infarction is a rare cause of neurologic deterioration after cervical spine decompressive surgery. Proposed causes of ischemic events include intraoperative or postoperative hypotension, or decreased venous return in conjunction with elevated vertebral venous pressures, which reduces arterial perfusion when patients undergo surgery in the prone position. Neuro-imaging is pivotal to exclude reversible causes for neurologic changes and confirmation of spinal cord infarction. We report five patients who underwent cervical decompressive surgeries and developed persistent postoperative neurological deficits compatible with spinal cord infarctions and evaluate causes for these rare complications. Methods The clinical courses and imaging studies of five patients were retrospectively analyzed. Imaging findings, types of surgeries, vascular compromise or risk factors, hypotensive episodes, intraoperative somatosensory evoked potentials, concomitant brain infarctions, and clinical degree and radiographic extent of spinal cord infarction were studied. Spinal cord infarctions were determined by clinical courses and imaging evaluations. Results All five patients had antecedent cervical cord region vascular compromise or generalized vascular risk factors. Four patients developed hypotensive episodes: two intraoperatively and two postoperatively. None of the four patients with hypotensive episodes had imaging or clinical evidence of concomitant brain infarctions. Conclusions The neuroimaging evaluation of spinal cord infarction after decompressive surgery is to exclude spinal cord compression, to ensure adequate surgical decompression, and to confirm infarction by imaging. The authors propose that antecedent, unrecognized preoperative vascular compromise may be a significant contributor to spinal cord infarction by itself, or in combination with hypotension.






Gene Therapy for Psychiatric Disorders

Available online 23 December 2012
Publication year: 2012
Source:World Neurosurgery

Gene therapy has become of increasing interest in clinical neurosurgery with the completion of numerous clinical trials for Parkinson's disease, Alzheimer's disease and pediatric genetic disorders. With improved understanding of the dysfunctional circuitry mediating a variety of psychiatric disorders, deep brain stimulation for refractory psychiatric diseases is being increasingly explored in human patients. This combination of factors is therefore likely to facilitate development of gene therapy for psychiatric diseases. Since delivery of gene therapy agents will require the same surgical techniques currently being employed for deep brain stimulation, neurosurgeons will likely lead the development of this field as has occurred in other areas of clinical gene therapy for neurological disorders. Here we will review the current state of gene therapy for psychiatric disorders, and will focus specifically upon particular areas of promising research that may translate into human trials for depression, drug addiction, obsessive-compulsive disorder and schizophrenia. Issues that are relatively unique to psychiatric gene therapy will also be discussed.






The Most Popular Scientific American Stories of 2012

The top 10 most popular stories published in 2012:

The Most Popular Scientific American Stories of 2012

Here are the stories you clicked on the most on our site


young men and women posing togetherRELATIONSHIPS beat guinea worms as our most popular story published in 2012.Image: skodonnell /iStockphoto

The top 10 most popular stories published in 2012:

1. Men and Women Can't Be "Just Friends"

2. The World's Last Worm: A Dreaded Disease Nears Eradication

3. NASA Crushes 2012 Mayan Apocalypse Claims 

4. How Hollywood Is Encouraging Online Piracy

5. Scientists Discover Children's Cells Livingin Mothers' Brains

6. Psychiatry's "Bible" Gets an Overhaul 


7. "Once in a Civilization" Comet to Zip Past Earth Next Year

8. The Power of Introverts: A Manifesto for Quiet Brilliance 


9. Obama and Romney Tackle 14 Top Science Questions

10. North Carolina Considers Making Sea Level Rise Illegal 



[More]

Add to digg Add to StumbleUpon Add to Reddit Add to Facebook Add to del.icio.us Email this Article