Publication year: 2011
Source: Journal of Clinical Neuroscience, Available online 5 December 2011
Jun Cai, Chuan He, Falei Yuan, Lujia Chen, Feng Ling
Cerebral aneurysms of traditional animal models are usually too small to be imagedin vivo. A novel rat model induced by ligation of the unilateral common carotid artery and contralateral pterygopalatine and external carotid arteries was investigatid. To evaluate the morphological changes of the cerebral arteries, synchrotron radiation angiography was utilised at 1 month, 2 months and 3 months after induction. Cerebral aneurysms and expansion of anterior cerebral arteries in these rats were identified when the animals were alive. This novel model is useful for cerebral aneurysm research.
Júlio Leonardo B. Pereira
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