Neurodegenerative disorders: Microglia get ready, set...
Nature Reviews Neuroscience 13, 154 (2012). doi:10.1038/nrn3189
Author: Sian Lewis
Primed microglia are associated with accelerated decline in patients with neurodegenerative diseases, and a new study indicates that the dysregulation of certain proteins of the alternative complement pathway might trigger the priming process.
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