Introduction
Normal pressure hydrocephalus (NPH) is a potentially treatable form of dementia characterised by a triad of symptoms (dementia, gait disturbance and urinary incontinence).
This triad is not pathognomic and may also be seen in other degenerative brain diseases (DBD). Diagnosis of NPH is based upon the clinical history/physical examination, brain imaging and CSF dynamics evaluation.1 The regional cerebral metabolic rate for glucose (rCMRglu) has been extensively measured in DBD. However, few PET studies describe a heterogeneous pattern of metabolic alterations in NPH and there is no conclusive evidence at present of an increase in metabolism after insertion of a CSF shunt.2 3
This is a preliminary study reporting changes in PET rCMRglu in patients with NPH before and after insertion of a shunt.
Materials and methods
Between October 2008 and November 2009, 10 patients with suspected idiopathic NPH were admitted to...
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