Monday, April 23, 2012

Lack of Increase in Intracranial Pressure After Epidural Blood Patch in Spinal Cerebrospinal Fluid L

Abstract
Background and Importance  
Epidural blood patch (EBP) is one therapeutic measure for patients suffering from spontaneous intracranial hypotension (SIH) or post-lumbar puncture headaches. It has been proposed that an EBP may directly seal a spinal cerebrospinal fluid (CSF) fistula or result in an increase in intracranial pressure (ICP) by a shift of CSF from the spinal to the intracranial compartment. To the best of our knowledge this is the first case of a patient with SIH and neurological deterioration in whom ICP was measured before, during, and after spinal EBP.
Clinical Presentation  
This 52-year old previously healthy man presented with holocephal headaches. MRI showed a left hemispheric subdural fluid collection causing a significant mass effect. Myelography revealed a CSF leak with epidural contrast at the left side of the L-2 level. To seal the CSF leak, we performed an EBP procedure targeted at left L-2 level and recorded ICP. After applying the epidural blood patch (15 cc) the patient improved rapidly, ICP however remained unchanged before, during, and after the procedure. One day post-treatment, he had a GCS score increase from 12 to 15 and no headache or neurological deficits.
Conclusion  
A shift of CSF from the spinal to the cranial compartment with a subsequent rise in ICP might not be a beneficial therapeutic mechanism of spinal epidural blood patching.

  • Content Type Journal Article
  • Category Practical Pearl
  • Pages 1-6
  • DOI 10.1007/s12028-012-9702-4
  • Authors
    • Jens Fichtner, Department of Neurosurgery, Bern University Hospital, Publications Office, 3010 Bern, Switzerland
    • Christian Fung, Department of Neurosurgery, Bern University Hospital, Publications Office, 3010 Bern, Switzerland
    • Werner Z`Graggen, Department of Neurosurgery, Bern University Hospital, Publications Office, 3010 Bern, Switzerland
    • Andreas Raabe, Department of Neurosurgery, Bern University Hospital, Publications Office, 3010 Bern, Switzerland
    • Jürgen Beck, Department of Neurosurgery, Bern University Hospital, Publications Office, 3010 Bern, Switzerland





No comments:

Post a Comment