Publication year: 2012
Source:Journal of Clinical Neuroscience
Bradley A. Gross, Kai U. Frerichs, Rose Du
An increasing number of patients with arteriovenous malformations (AVM) are being screened with expedient, safe, and non-invasive methods such as computed tomography angiography (CTA), MRI, and magnetic resonance angiography (MRA). Only a paucity of small series have examined the sensitivity of these modalities in detecting AVMs. In this study, we reviewed 125 patients with AVMs, demonstrating overall sensitivities of 90% for CTA, 89% for T2-weighted MRI, and 74% for MRA. The greater sensitivity of CTA in detecting AVMs compared to MRA did meet statistical significance (p CTA, MRA =0.036). For unruptured AVMs, the sensitivities were 96%, 97% and 71% (p CTA, MRA =0.043) and for ruptured AVMs, they were 87%, 83% and 77%, respectively. The sensitivity was 100% for both CTA and T2-weighted MRI for AVMs larger than 3cm. Importantly, associated aneurysms were best detected via CTA, with a sensitivity of 88%, as compared to 29% for MRI and 27% for MRA (p CTA, MRA =1.2×10−6), with the greatest distinction occurring within the subgroup of intranidal aneurysms with a sensitivity of 83% for CTA compared to 0% for both MRI and MRA (p CTA, MRA =0.005).
Júlio Leonardo B. Pereira
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