Thursday, October 4, 2012

Current status of Pipeline Embolization Device in the treatment of intracranial aneurysms – A review

Publication year: 2012
Source:World Neurosurgery
Mona M.Y. Tse, Bernard Yan, Richard J Dowling, Peter J Mitchell
Objective Pipeline Embolization Device (PED) implantation is a novel endovascular treatment option for intracranial aneurysms. It is emerging as a useful alternative to coiling and to open surgery and its use is increasing worldwide. We have performed a literature review to examine its efficacy, technical challenges and safety. Method Pubmed database was used to identify all articles relating to PED. Result The review outlines the indications for PED, its technical aspects, complications and clinical outcomes. Conclusion PED offers an alternative to endovascular coiling for aneurysms with complex morphology. The indication for its use has evolved from the limited scope of treatment of giant aneurysms with wide necks, to the inclusion of smaller aneurysms. The procedural safety profile of PED is comparable or possibly superior to balloon-remodeling or stent-assisted coil embolization in specific circumstances. However, questions remain regarding the incidence of post-procedural subarachnoid hemorrhage. Ongoing monitoring and meticulous documentation of PED post-implantation safety is strongly recommended.






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