Publication year: 2012
Source:Journal of Clinical Neuroscience
Sai-Cheung Lee, Yi-Chou Wang, Yin-Cheng Huang, Po-Hsun Tu, Shih-Tseng Lee
Decompressive craniectomy has been considered the most attractive option for surgical treatment of malignant middle cerebral artery (MCA) infarction. We retrospectively reviewed the clinical and radiological records of 78 patients with malignant MCA infarction who underwent decompressive craniectomy with dura augmentation over a 6-year period. Twenty-six patients had undergone additional anterior temporal resection during decompressive craniectomy. The overall mortality at 30days after surgery was 25.6% while the mortality rate at 6months after surgery was 30.8%. At 6months after surgery, 30.8% of the patients were considered to have good outcomes, while 69.2% had a poor outcome (16.7% suffered from severe disability, 21.8% remained in a vegetative state, and 30.8% died). Ipsilateral surgery was performed on 48 patients with infarction on the dominant side and on 30 patients with lesions on the non-dominant side. No significant difference was noted between these two groups at the 30-day mortality rate. Although no patient with an infarction on the dominant side recovered effective verbal ability during the 6months of follow-up, there was no significant difference between the two groups in clinical outcome at 6months after surgery. The 30-day survival rate in the 26 patients who underwent additional anterior temporal lobectomy was significantly higher (84.6%) than that in patients who underwent decompressive craniectomy and duroplasty only (69.2%) (p <0.05). However, in patients who survived, this additional procedure does not appear to improve the functional outcome.
Júlio Leonardo B. Pereira
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