Nature Reviews Neuroscience 14, 77 (2013). doi:10.1038/nrn3425
Author: Rachel Jones
Childhood trauma can predispose people with certain genotypes to disorders such as post-traumatic stress disorder in adulthood. Now, Klengel et al. show that a particular polymorphism in a gene involved in glucocorticoid regulation can interact with childhood trauma, leading to lasting epigenetic changes in the stress response system.
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