Teaching NeuroImages: A neurosyphilis case presenting with atypical neuroradiologic findings

A 51-year-old man presented with memory loss, behavioral changes, and generalized seizures for 4 months. Mini-Mental State Examination (MMSE) score was 11. MRI showed hyperintensities in multiple cortical areas and thalami (figure, A–C). Diffusion was restricted in certain areas (figure, D and E). Treponemal antibody tests were positive in serum and CSF. He was treated with penicillin. Six months later, his behavior and memory improved considerably (MMSE 20).

http://www.neurology.org/cgi/content/short/80/11/e119?rss=1

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Júlio Leonardo B. Pereira

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