Surgical Resection of Cavernous Malformations of the Brainstem: Evolution of a Minimally Invasive Te

Publication date: May–June 2013
Source:World Neurosurgery, Volume 79, Issues 5–6
Author(s): Jeffrey C. Mai , Dinesh Ramanathan , Louis J. Kim , Laligam N. Sekhar
Objective The purpose of this study is to provide an institutional retrospective review of surgically treated brainstem cavernous malformations. Methods Between 2005 and 2010, 22 consecutive patients with brainstem cavernous malformations (15 female and 7 male) with a mean age of 43 years underwent surgical treatment. Mean volume of the resected cavernous malformations was 0.65 cm³. A minimally invasive resection technique was used for these cases, in conjunction with skull base approaches. Results The mean follow-up period was 26.6 months (range, 4-68 months). Of the 22 patients, 9% did not have clear evidence of hemorrhage at the time of presentation. Of the remainder, 22% had two or more instances of hemorrhage documented by magnetic resonance imaging. After resection and during follow-up, 54% of patients had an improvement in their modified Rankin scale, whereas 14% were worse compared with their preoperative presentation; 32% were unchanged and 9% of patients were found to have residual cavernoma post-surgery. Conclusion Our longitudinal experience has guided us to emphasize minimally invasive approaches during resection of the brainstem cavernous malformations, occasionally at the expense of achieving a complete resection, to improve patient outcomes.

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