De novo arteriovenous malformation after brain radiotherapy for medulloblastoma in a child

De novo arteriovenous malformation after brain radiotherapy for medulloblastoma in a child

Neurology recent issues

A 5-year-old boy was operated on for a non-metastatic medulloblastoma of the fourth ventricle (figure 1). Chemotherapy and bifractionated craniospinal radiotherapy were administered. Four years later, T1-weighted MRI with contrast revealed abnormal vessels in the right sylvian fissure that gradually increased during follow-up; angiography confirmed an arteriovenous malformation (AVM) (figure 2). Even though it was asymptomatic, its location and growth prompted us to treat (embolization then excision of the residual nidus). This very rare case of supposed radiation-induced AVM suggests that when abnormal vasculature imaging occurs in follow-up^1,2 further investigation with angiography is warranted, with consideration of further treatment.

Original Article: http://www.neurology.org/cgi/content/short/81/4/398?rss=1

Julio Pereira, MD

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