Neuroimaging Findings in Pediatric Propofol Infusion Syndrome

Neuroimaging Findings in Pediatric Propofol Infusion Syndrome

Pediatric Neurology

A 3-year-old girl with a large venous malformation involving tongue, lips, and masticator space underwent sclerotherapy during propofol anesthesia. After the procedure, she developed metabolic acidosis with acute renal failure, rhabdomyolysis, and transient neurological deficits including encephalopathy and weakness of arms and legs. This constellation of findings in a child with propofol anesthesia suggests propofol-related infusion syndrome (PRIS). Acute brain magnetic resonance imaging showed T2-hyperintensity and reduced diffusion on apparent diffusion coefficient maps within the supra- and infratentorial white matter (); these changes had completely resolved at follow-up. Three months after the acute event, all symptoms and clinical findings completely resolved.

Original Article: http://www.pedneur.com/article/S0887-8994(13)00754-6/abstract?rss=yes

Julio Pereira 
www.neurocirurgiabr.com
http://www.linkedin.com/in/juliommais
http://lattes.cnpq.br/7687651239699170
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