[Review] Current concepts and clinical applications of stroke genetics
The Lancet Neurology
Driven by innovative technologies, novel analytical methods, and collaborations unimaginable not long ago, our understanding of the role of genetic variation in stroke has advanced substantially in recent years. However, a vast amount of data have accumulated quickly, and increasingly complex methodologies used in studies make keeping up to date on relevant findings difficult. In addition to well known, highly penetrant rare mutations that cause mendelian disorders related to stroke, several common genetic variants have been associated with common stroke subtypes, some of which also affect disease severity and clinical outcome.
Original Article: http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(14)70029-8/abstract?rss=yes
Julio PereiraConsultório (11) 3141-9550 / 3141-9553
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