OBJECTIVE: The aim of this study was to explore gender differences in clinical characteristics (likelihood of percutaneous endoscopic gastrostomy PEG tubes and development of aspiration pneumonia) and outcomes in patients with intracerebral hemorrhage (ICH) by using the data from the Nationwide Inpatient Sample.BACKGROUND: Gender differences following ischemic strokes are well described, however little is known about gender differences in outcomes in patients following an ICH. Dysphagia and aspiration pneumonia are common complications following ICH. If persistent, alternate means of nutrition such as a PEG tube and continuous respiratory care measures may be undertaken, which can affect discharge outcomes in surviving patients.DESIGN/METHODS: We reviewed data from the Nationwide Inpatient Sample database for patients with intracerebral hemorrhage (ICD Code 431) between 2008 and 2010. Demographic, clinical complications (freqency of PEG insertion and aspiration) and discharge outcome (death, home discharge) were gathered. Univariate and multivariate analyses were performed to explore gender differences in outcomes.RESULTS: Of 56,617 patients, 50.4% were male (mean age 65) of which 24.7% died while among females (mean age 70), 26% died (p=0.0005). Survival trends from ICH are improving for both men and women. Among the survivors, women have 17% lower odds of going home (p<0.0001). After adjustment for age, women still have significantly lower odds of going home if they survive the ICH. During hospitalization with ICH, women have 16% lower odds of getting a PEG tube (p<0.0001) and 37% lower odds of developing aspiration pneumonia (p<0.0001) when compared with men.CONCLUSION: Our study indicates a less favourable outcome for women with ICH compared to men. Reasons for the differences are probably biological as well as social and cultural; and need to be addressed in future studies
Disclosure: Dr. Varade has nothing to disclose. Dr. Bhattacharya has nothing to disclose.
Original Article: http://www.neurology.org/cgi/content/short/82/10_Supplement/P2.143?rss=1
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