Original Article: http://journals.lww.com/neurosurgery/Fulltext/2014/11000/Magnetic_Resonance_Imaging_Measures_of_Posterior.4.aspx
Monday, October 27, 2014
Magnetic Resonance Imaging Measures of Posterior Cranial Fossa Morphology and Cerebrospinal Fluid Physiology in Chiari Malformation Type I
Original Article: http://journals.lww.com/neurosurgery/Fulltext/2014/11000/Magnetic_Resonance_Imaging_Measures_of_Posterior.4.aspx
The Role of Antiplatelet Medications in Angiogram-Negative Subarachnoid Hemorrhage
Original Article: http://journals.lww.com/neurosurgery/Fulltext/2014/11000/The_Role_of_Antiplatelet_Medications_in.6.aspx
Phase I Clinical Trial for the Feasibility and Safety of Remote Ischemic Conditioning for Aneurysmal Subarachnoid Hemorrhage
Original Article: http://journals.lww.com/neurosurgery/Fulltext/2014/11000/Phase_I_Clinical_Trial_for_the_Feasibility_and.13.aspx
Can ADHD Really Be Diagnosed by EEG?
Selim R. Benbadis about the clinical utility of using electroencephalography to diagnose ADHD.
Medscape Neurology
Original Article: http://www.medscape.com/viewarticle/833407?src=rss
ICU Physician-Based Determinants of Life-Sustaining Therapy During Nights and Weekends: French Multicenter Study From the Outcomerea Research Group*
Original Article: http://journals.lww.com/ccmjournal/Fulltext/2014/11000/ICU_Physician_Based_Determinants_of.10.aspx
A Review of Episodic and Chronic Pediatric Headaches of Brief Duration
Headaches that last less than one hour in duration are uncommon, except for atypical migraine, and, without a practitioner's appropriate knowledge, may result in misdiagnosis. Although most of these headaches are classified as primary headache syndromes, some have secondary etiologies such as structural lesions. This pediatric-specific review updates these headache syndromes. Discussed are atypical migraine, the trigeminal autonomic cephalgias (TAC), cranial neuralgias, occipital neuralgia, thunderclap headache, nummular headache, the red ear syndrome and the numbtongue syndrome.
Original Article: http://www.pedneur.com/article/S0887-8994(14)00649-3/abstract?rss=yes
Has Your Smartphone Made Your Other Gadgets Obsolete? [Survey]
Tell us how you use your smartphone, which gadgets it has replaced and where you would like to see the technology go
-- Read more on ScientificAmerican.com
Original Article: http://www.scientificamerican.com/article/has-your-smartphone-made-your-other-gadgets-obsolete-survey/
Cerebrovascular regulation, exercise, and mild traumatic brain injury
A substantial number of people who sustain a mild traumatic brain injury report persistent symptoms. Most common among these symptoms are headache, dizziness, and cognitive difficulties. One possible contributor to sustained symptoms may be compromised cerebrovascular regulation. In addition to injury-related cerebrovascular dysfunction, it is possible that prolonged rest after mild traumatic brain injury leads to deconditioning that may induce physiologic changes in cerebral blood flow control that contributes to persistent symptoms in some people. There is some evidence that exercise training may reduce symptoms perhaps because it engages an array of cerebrovascular regulatory mechanisms. Unfortunately, there is very little work on the degree of impairment in cerebrovascular control that may exist in patients with mild traumatic brain injury, and there are no published studies on the subacute phase of recovery from this injury. This review aims to integrate the current knowledge of cerebrovascular mechanisms that might underlie persistent symptoms and seeks to synthesize these data in the context of exploring aerobic exercise as a feasible intervention to treat the underlying pathophysiology.
Original Article: http://www.neurology.org/cgi/content/short/83/18/1665?rss=1
Hospital Case Volume Is Associated With Mortality in Patients Hospitalized With Subarachnoid Hemorrhage
Original Article: http://journals.lww.com/neurosurgery/Fulltext/2014/11000/Hospital_Case_Volume_Is_Associated_With_Mortality.2.aspx
Thursday, October 23, 2014
Brain simulation raises questions
What does it mean to simulate the human brain? Why is it important to do so? And is it even possible to simulate the brain separately from the body it exists in?
Original Article: http://www.medicalnewstoday.com/releases/284244.php
Wednesday, October 22, 2014
The Changing Role of Palliative Care in the ICU
Original Article: http://journals.lww.com/ccmjournal/Fulltext/2014/11000/The_Changing_Role_of_Palliative_Care_in_the_ICU.13.aspx
Critical Care Telemedicine: Evolution and State of the Art*
Original Article: http://journals.lww.com/ccmjournal/Fulltext/2014/11000/Critical_Care_Telemedicine___Evolution_and_State.14.aspx
Epilepsy surgery in children and adults.
- Ryvlin P, Cross JH, Rheims S
- Epilepsy surgery in children and adults. [REVIEW]
- Lancet Neurol 2014 Nov; 13(11):1114-1126.
Original Article: http://www.unboundmedicine.com/medline/citation/25316018/Epilepsy_surgery_in_children_and_adults_
Expanding the antibody spectrum of limbic encephalitis!
Limbic encephalitis (LE) mat have an underlying autoimmune etiologiy. over the last decade numerous antibodies have emerged as potenital causative agents, and the antibodies have been directed against external epitopes of specific receptors. In an upcoming issue of JNNP, Onugoren and colleagues reaffirm the association between GABAB and AMPR receptor antibodies and LE. Importantly neoplastic causes need to be considered.
Read more at : http://jnnp.bmj.com/content/early/2014/10/09/jnnp-2014-308814.full
Typical MRI changes in LE
Original Article: http://blogs.bmj.com/jnnp/2014/10/17/expanding-the-antibody-spectrum-of-limbic-encephalitis/
Carpal tunnel syndrome in a child with Down Syndrome
Recently, Davis en Vedanarayanan gave an overview of the carpal tunnel syndrome in Pediatric Neurology. (1) This neuropathy of the median nerve causes numbness, paresthesias, and pain in the hands. Symptoms occur mostly during the night and disrupt normal sleep. The carpal tunnel syndrome is present in almost all children with mucopolysaccharidosis, but otherwise it is rare in childhood. Recently we encountered the carpal tunnel syndrome in a child with Down syndrome.
Original Article: http://www.pedneur.com/article/S0887-8994(14)00534-7/abstract?rss=yes
The Value of 3T MRI in Acute Transverse Myelitis
An 11 year old girl presented with 18 hours of right leg weakness and left leg numbness. Past medical history was significant for a two day viral gastroenteritis 25 days prior and vaccinations 24 days prior (Tetanus, diphtheria, and pertussis; human papilloma virus; influenza; and meningococcal). Initial exam pertinent findings were right leg weakness (0/5 proximally and 3/5 distally), absent left leg temperature sense to the groin area without anesthesia or left hemibody sensory level, and inconsistent decreased right patellar reflex and extensor plantar response.
Original Article: http://www.pedneur.com/article/S0887-8994(14)00462-7/abstract?rss=yes
Pediatric Migraine Prescription Patterns at a Large Academic Hospital
Here we report the prescription patterns by drug type, age, and sex of patients at a large academic pediatric hospital. Because there are few guidelines based on outcome studies in pediatric migraine, physician treatment approaches in children vary.
Original Article: http://www.pedneur.com/article/S0887-8994(14)00394-4/abstract?rss=yes
Pregabalin Treatment in a Case with Complex Regional Pain Syndrome
Complex regional pain syndrome (CRPS) is a painful and disabling neurovascular condition. There is no definite consensus on the etiopathogenesis and treatment. We present a case diagnosed with CRPS type 1 accompanied by a psychiatric disorder to discuss the relationship between CRPS and psychiatric disease and to emphasize the response of this case to pregabalin treatment.
Original Article: http://www.pedneur.com/article/S0887-8994(14)00016-2/abstract?rss=yes
Comment: How personal is Alzheimer disease?
Personality has long been recognized as important in Alzheimer disease (AD), although primarily in terms of exaggeration or diminishment of preexisting traits around the clinical onset. The findings reported by Johansson et al. in this issue further suggest that there may be traits, neuroticism in this case, that are associated with increased risk of AD. The long interval (nearly 40 years) between onset of neuroticism and outcome (AD) rules out any effect of early AD pathology, which has been a perennial limitation of shorter-term studies of depressive symptoms as a risk factor. Selective survival is also an unlikely explanation because stress and early cognitive decline are both likely to predict mortality and thus obscure the association of interest—indeed, it is surprising how many risk factors for mortality are also found to be risk factors for AD despite this bias.
Original Article: http://www.neurology.org/cgi/content/short/83/17/1542?rss=1
Mental rest and reflection 'boost learning'
New research finds that restful reflection can strengthen memories in the mind and forge new mental connections, priming the brain for future learning.
Original Article: http://www.medicalnewstoday.com/articles/284165.php
Can Video Games Diagnose Cognitive Deficits?
This blog is the third in a series of guest posts on technology and the brain to celebrate Scientific American Mind's 10-year anniversary.
-- Read more on ScientificAmerican.com
Original Article: http://www.scientificamerican.com/blog/post/can-video-games-diagnose-cognitive-deficits/
Paralyzed Man Walks After Cell Transplant Into Spinal Cord
A man who was paralyzed after a knife stabbing is walking after surgery that involved transplanting cells taken from his olfactory lobe into his severed spinal cord.
Medscape Medical News
Original Article: http://www.medscape.com/viewarticle/833663?src=rss
Congress of Neurological Surgeons (CNS) 2014 Annual Meeting
Read clinically focused news coverage of key developments from CNS 2014.
Medscape Neurology
Original Article: http://www.medscape.com/viewcollection/33234?src=rss
New 3-Minute Delirium Test
The shortened test demonstrates high sensitivity and specificity compared with a longer reference standard, a new study shows
Medscape Medical News
Original Article: http://www.medscape.com/viewarticle/833600?src=rss
Wednesday, October 15, 2014
Injury to brain 'hubs' does more damage
A new study shows that more mental functions are impaired by damage to brain hubs - where several networks come together - compared with brain damage that is far from hubs.
Original Article: http://www.medicalnewstoday.com/articles/283850.php
Dysregulation in orexinergic system associated with Alzheimer disease
In patients with Alzheimer disease (AD), increased cerebrospinal fluid levels of orexin, which helps regulate the sleep-wake cycle, may be associated with sleep deterioration, which appears to be...
Original Article: http://www.medicalnewstoday.com/releases/283805.php
Stenting safe and effective for long-term stroke prevention
Using stents to keep neck arteries open is just as effective as invasive neck surgery for long-term prevention of fatal and disabling strokes, reports an international trial led by UCL (University...
Original Article: http://www.medicalnewstoday.com/releases/283852.php
Tuesday, October 14, 2014
[Comment] Therapy of amyotrophic lateral sclerosis remains a challenge
Amyotrophic lateral sclerosis is a devastating fatal disease of motor neurons in the brain, brainstem, and spinal cord. It affects otherwise healthy people and can develop at any point in adulthood. Worldwide, more than 150 000 people die from the disease every year, on average 3 years after symptom onset. Laboratory and patient-oriented research during the past two decades has led to major improvements in our understanding of the pathogenesis of amyotrophic lateral sclerosis, including newly discovered genes, improved in-vitro and in-vivo modelling of the disease, generation of patient-derived motor neurons through induced pluripotent stem cell technology, the discovery of TDP43 protein aggregates in motor neurons, innovative imaging and whole-genome sequencing technology initiatives, the identification of endophenotypes, and the association of the disease with frontotemporal dementia.
Original Article: http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(14)70179-6/fulltext?rss=yes
Concussion: Key Stakeholders and Multidisciplinary Participation in Making Sports Safe
Original Article: http://journals.lww.com/neurosurgery/Fulltext/2014/10001/Concussion___Key_Stakeholders_and.11.aspx