Friday, December 19, 2014

Misfiring in the brain's control system linked to OCD

Misfiring in the brain's control system linked to OCD
Neurology News & Neuroscience News from Medical News Today

Compulsions as a result of OCD may be down to the brain's control system misfiring, says a new study, adding evidence that OCD stems from an overactive habit system in the brain.

Original Article: http://www.medicalnewstoday.com/articles/287291.php

Monday, December 15, 2014

Refractory trigeminal neuralgia treatment outcomes following CyberKnife radiosurgery

Refractory trigeminal neuralgia treatment outcomes following CyberKnife radiosurgery
Radiation Oncology

IntroductionA handful of studies have reported outcomes with CyberKnife radiosurgery (CKRS) for the treatment of trigeminal neuralgia. However, the follow-up has been short with no minimum follow-up required and have included patients with short duration of symptoms. Here we report our institutional experience on patients with a minimum follow-up of 1?year and a median follow-up of 28?months (mean 38.84?months). Methods: Twenty-five patients with medically and surgically intractable TN received CKRS with a mean marginal radiation dose of 64?Gy applied to an average isodose line of 86% of the affected trigeminal nerve. Follow-up data were obtained by clinical examination and telephone questionnaire. Outcome results were categorized based on the Barrow Neurological Institute (BNI) pain scale with BNI I-III considered to be good outcomes and BNI IV-V considered as treatment failure. BNI facial numbness score was used to assess treatment complications. Results: A large proportion of patients (42.9%) reported pain relief within 1?month following CKRS treatment. The mean time to recurrence of severe pain was 27.8?months (range 1?129 months). At median follow-up of 28?months (mean 38.84?months), actuarial rate of freedom from severe pain (BNI???III) was 72%. At last follow-up 2 (8%) patients had freedom from any pain and no medications (BNI I) and the majority (48%) had some pain that was adequately controlled with medications. Seven patients (28%) had no response to treatment and continued to suffer from severe pain (BNI IV or V). Patient?s diabetic status and overall post-treatment BNI facial numbness scores were statistically significant predictors of treatment outcomes. Conclusion: CKRS represents an acceptable salvage option for with medically and/or surgically refractory patients. Even patients with severely debilitating symptoms may experience significant and sustained pain relief after CKRS. Particularly, CKRS remains an attractive option in patients who are not good surgical candidates or possibly even failed surgical therapy. This data should help in setting realistic expectations for weighing the various available treatment options.

Original Article: http://www.ro-journal.com/content/9/1/257

fMRI detects neural injury due to HIV before symptoms occur

fMRI detects neural injury due to HIV before symptoms occur
Neurology News & Neuroscience News from Medical News Today

A five-minute functional MRI (fMRI) test can pick up neuronal dysfunction in HIV-positive individuals who don't yet exhibit cognitive decline, say neuroscientists and clinicians at Georgetown...

Original Article: http://www.medicalnewstoday.com/releases/286830.php

Neurosurgery TV: Telemedicine - "Reacts" platform. Neurosurgery Internet TV Weekly

Neurosurgery TV: Telemedicine - "Reacts" platform. Neurosurgery Internet TV Weekly

Check out this video on YouTube:

http://youtu.be/dMY7lilzOTU