Neuroimmunology: Does multiple sclerosis originate in the gut?
Nature Reviews Neuroscience 12, 706 (2011). doi:10.1038/nrn3150
Author: Darran Yates
Autoreactive T and B cells may have important roles in multiple sclerosis, but what triggers autoreactivity is unclear. Here, the authors examined a relapsing–remitting variant of spontaneously developing murine experimental autoimmune encephalomyelitis (EAE). In this multiple sclerosis model, disease is driven by T cells that
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