Thursday, February 9, 2012

Increased risk of stroke after Bell's palsy: a population-based longitudinal follow-up study

Bell's palsy (BP) has been related to inflammation and oedema of the facial nerve, leading to focal ischaemia and demyelination. Serological and PCR studies have suggested that BP is related to reactivation of herpes simplex virus type 1 (HSV-1) and varicella-zoster viruses (VZVs).1 2 Because the infectious burden of certain viruses of the herpes virus family has been associated with an increased risk of stroke,3 we sought to investigate whether there is an increased risk of stroke after BP.

Material and methods

The data used in this study were taken from the complete National Health Insurance (NHI) claim database in Taiwan from 2000 to 2003. This study included a BP cohort and a non-BP cohort, both of which were selected from Taiwanese residents retrieved from the complete NHI claim database for 2001, in which more than 21.6 million persons were registered. To determine...






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